Skip to main content
Back to Top


Toxic stress and protective factors in multi-ethnic school age children: A research protocol

Date Added to Library: 
Wednesday, February 13, 2019 - 14:07
Digital Object Identifier (DOI): 
Individual Author: 
Condon, Eileen M.
Sadler, Lois S.
Mayes, Linda C.
Reference Type: 
Published Date: 
Published Date (Date): 
Wednesday, February 14, 2018
Research in Nursing and Health
Issue Number: 
Page Range: 

Exposure to stressful environments in early childhood can cause a toxic stress response and lead to poor health outcomes, including obesity, cardiac disease, diabetes, and mental illness. In animals and maltreated children, the presence of a nurturing caregiver can buffer against the physiological disruptions associated with a toxic stress response; however, the specific caregiver and parenting characteristics that best promote a protective relationship in humans remain largely unexplored, particularly in families living in high-risk environments. In this study, framed in an ecobiodevelopmental (EBD) model, a cross-sectional design is being used to study 54 multi-ethnic, urban maternal-child dyads with children at early school age (4-9 years). Mothers past experiences, mental health, and caregiving patterns and children's hair cortisonl, C-reactive protein, pro-inflammatory cytokines, blood pressure, BMI, behavior, and school performance are being analyzed to identify maternal characteristics that may protect against children's toxic stress response in families at high risk for exposure to stressors such as poverty, trauma, or exposure to violence. (Author abstract)

Geographic Focus: 
Page Count: 
Topical Area: 

The SSRC is here to help you! Do you need more information on this record?

If you are unable to access the full-text of the article from the Public URL provided, please email our Librarians for assistance at

In addition to the information on this record provided by the SSRC, you may be able to use the following options to find an electronic copy from an online subscription service or your local library:

  • Worldcat to find an electronic copy from an online subscription service
  • Google Scholar to discover other full text options